What are the ingedients of a good, even perfect Epigenetic Study design? Prof Carlo Schuengel guides us in a simple, yet very effective way down the lanes of how to choose what you need and then how you put them together for the big outcome. He introduces us some “exotic” vocabulary when speaking about the various stages when we plan our study. Then, he speaks about how to formulate the purpose of the study telling us about description and prediction, precision and accuracy, the generalizability and caudal modeling among others and guides us as to how to collect longitudinal and follow-up data. Finally, using good and very good examples of epigenetic study design, he helps us actually consolidate the knowledge shared about the strategy, practicalities, risks and opportunities.
Prof Carlo Schuengel is a Full Professor, Faculty of Behavioral and Movement Sciences, Clinical Child and Family Studies at Vrije University in Amsterdam, Netherlands. Prof Schuengel aims to contribute insights into family relationships and the development of mental health and resilience, and into interventions that can support at risk parents and other caregivers in fostering high quality relationships with children. This goal is pursued by a combination of research on the Generations2 longitudinal pregnancy cohort study, creation and synthesis of practice-based and research-based evidence, and intervention studies in partnership with intervention services and care organizations that support families, children, and people with disabilities. Attachment theory has been a major theoretical basis for this work since the program started in 2000.
Epigenetic studies in Developmental Origins of Health and Disease: pitfalls and key considerations for study design and interpretation by L. Yamada and S. Chong
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Developmental cascades by ANN S. MASTEN & DANTE CICCHETTI